Jennifer Scheinman, MS, RDN, completed her dietetic internship at New York-Presbyterian Weill Cornell Medical Center and went on to complete her master’s degree in Integrative and Functional Nutrition at Saybrook University.

Over the past 20 years she has worked at some of the country’s leading institutions for health and wellness, including Hospital for Special Surgery and Optum, where she led the creation of nutrition and health education programs that positively impacted thousands of people’s lives.  

Jen currently is the Senior Manager of Nutrition Affairs at Timeline Nutrition, educating healthcare practitioners and consumers on the latest scientific breakthroughs in healthy aging.

[Sponsor Message: This podcast is sponsored by Nutrisense, a revolutionary health focused company that helps you maintain healthy blood sugar levels with a continuous glucose monitor and dietitian support.

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02:30 Jen’s Background

  • Registered dietitian, been in health and wellness for over 20 years

03:47 What Are Mitochondria and Why Are They Important

  • Little organelles that generate cellular energy
  • This energy powers our heart beating, lungs breathing and everything else
  • As they produce energy, they get damaged in the process

05:15 What Happens To Mitochondria As We Age

  • Mitochondria wear themselves out so they produce less energy
  • Our body has a process called Mitophagy, where the damaged mitochondria regenerate themselves
  • This helps create rejuvenated mitochondria and repairs a lot of the damage
  • In addition, the mitophagy process also slows down as we age
  • Linked to chronic conditions such as muscle loss, neurodegenerative issues, cardiac issues

08:35 At What Age Does The Mitochondrial Decline Start?

  • Happening a lot earlier than we think
  • Starts in our 30’s
  • It’s correlated with muscle loss as we get older

11:03 How Can We Encourage The Mitophagy Process?

  • There are 3 main ways to increase mitophagy
  • Fasting
  • Exercise
  • A substance called Urolithin A

15:50 What Is Urolithin A And How Is It Produced?

  • Discovered 14 years ago, researchers have been studying it since
  • Amazentis, their science arm, has been researching Urolithin A
  • Derived from pomegranate, but the gut makes urolithin A from eligatannins in pomegranate
  • Urolithin A is then used by your body
  • You need the right microbiome to make Urolithin A
  • After studies, less than 40% of the population are making Urolithin A

18:50 Mitopure Challenge

  • Simple blood test to figure out if you can make Urolithin A from pomegranate juice
  • You test with pomegranate juice and with Urolithin A

21:00 How Long Do People See Results With Mitopure

  • At one month, there are changes in mitochondria and they look healthier
  • At month 2 and 4 months, there are improvements in muscular strength, performance and endurance
  • Some people see an effect in 2 weeks, others see results in month 2 or 3
  • The process to rebuild the mitochondria takes a little bit of time
  • Consumers see improvements at gym, running faster and recovery seems to be better

23:50 Why The Research Is Measuring Muscle Health?

  • It’s easy to measure skeletal muscle health and improvement
  • Muscle health is correlated to aging – so that was the first target
  • Also looking at other systems in the body – immunity, cancer and more

26:00 What’s The Team Behind Mitopure?

  • Research team is based in Switzerland
  • They have a series of patents on Urolithin A
  • Amazentis is the research company, Timeline is the marketing company

29:33 Timeline’s New Products On Market

  • Just releasing a new skincare line
  • Urolithin A can also be absorbed into cell topically, so they’ve made creams and a serum

31:00 Where Can You Find Timeline Nutrition?

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